Synaptotagmin-2 Is Essential for Survival and Contributes to Ca(2+) Triggering of Neurotransmitter Release in Central and Neuromuscular Synapses

Biochemical and genetic data suggest that synaptotagmin-2 functions as a Ca(2+) sensor for fast neurotransmitter release in caudal brain regions, but animals and/or synapses lacking synaptotagmin-2 have not been examined. We have now generated mice in which the 5′ end of the synaptotagmin-2 gene was...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Pang, Zhiping P., Melicoff, Ernestina, Padgett, Daniel, Liu, Yun, Teich, Andrew F., Dickey, Burton F., Lin, Weichun, Adachi, Roberto, Südhof, Thomas C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2006
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674714/
https://ncbi.nlm.nih.gov/pubmed/17192432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3519-06.2006
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