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Combination of Thrombin and Matrix Metalloproteinase-9 Exacerbates Neurotoxicity in Cell Culture and Intracerebral Hemorrhage in Mice

The rapid loss of neurons is a major pathological outcome of intracerebral hemorrhage (ICH). Several mechanisms may produce the neurotoxicity observed in ICH, and these include proteolytic enzymes such as thrombin and matrix metalloproteinase-9 (MMP-9). We tested the hypothesis that thrombin and MMP...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Xue, Mengzhou, Hollenberg, Morley D., Wee Yong, V.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674619/
https://ncbi.nlm.nih.gov/pubmed/17021183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2806-06.2006
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