Tumor Necrosis Factor Receptor 1 Is a Negative Regulator of Progenitor Proliferation in Adult Hippocampal Neurogenesis

Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine, acting through the TNF-R1 and TNF-R2 receptors. The two receptors have been proposed to mediate distinct TNF-α effects in the CNS, TNF-R1 contributing to neuronal damage and TNF-R2 being neuroprotective. Whether TNF-α and its receptors p...

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Udgivet i:J Neurosci
Main Authors: Iosif, Robert E., Ekdahl, Christine T., Ahlenius, Henrik, Pronk, Cornelis J. H., Bonde, Sara, Kokaia, Zaal, Jacobsen, Sten-Eirik W., Lindvall, Olle
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2006
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674454/
https://ncbi.nlm.nih.gov/pubmed/16988041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2723-06.2006
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