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Inflammation is detrimental for neurogenesis in adult brain
New hippocampal neurons are continuously generated in the adult brain. Here, we demonstrate that lipopolysaccharide-induced inflammation, which gives rise to microglia activation in the area where the new neurons are born, strongly impairs basal hippocampal neurogenesis in rats. The increased neurog...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC263865/ https://ncbi.nlm.nih.gov/pubmed/14581618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2234031100 |
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