Chronic Unpredictable Stress Exacerbates Lipopolysaccharide-Induced Activation of Nuclear Factor-κB in the Frontal Cortex and Hippocampus via Glucocorticoid Secretion

Although the anti-inflammatory actions of glucocorticoids (GCs) are well established in the periphery, these stress hormones can increase inflammation under some circumstances in the brain. The transcription factor nuclear factor-κB (NF-κB), which is inhibited by GCs, regulates numerous genes centra...

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Publicado en:J Neurosci
Main Authors: Munhoz, Carolina Demarchi, Lepsch, Lucilia B., Kawamoto, Elisa Mitiko, Malta, Marília Brinati, Lima, Larissa de Sá, Werneck Avellar, Maria Christina, Sapolsky, Robert M., Scavone, Cristoforo
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674142/
https://ncbi.nlm.nih.gov/pubmed/16597735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4398-05.2006
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