Human Astrocytes Are Resistant to Fas Ligand and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis

Human astrocytes express Fas yet are resistant to Fas-induced apoptosis. Here, we report that calcium/calmodulin-dependent protein kinase II (CaMKII) is constitutively activated in human astrocytes and protects the cells from apoptotic stimulation by Fas agonist. Once stimulated, Fas recruits Fas-as...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Song, Jin H., Bellail, Anita, Tse, Margaret C. L., Yong, V. Wee, Hao, Chunhai
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674086/
https://ncbi.nlm.nih.gov/pubmed/16554480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5572-05.2006
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