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CD4 Regulates Susceptibility to Fas ligand– and Tumor Necrosis Factor–mediated Apoptosis

The current knowledge of CD4 function is limited to its role as a necessary coreceptor in TCR-initiated signaling. We have investigated whether CD4 regulates additional T cell functions. Using human primary resting CD4(+) T cells, we demonstrate that CD4 activation is sufficient to induce lymphocyte...

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Bibliografiske detaljer
Main Authors: Algeciras, Alicia, Dockrell, David H., Lynch, David H., Paya, Carlos V.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212167/
https://ncbi.nlm.nih.gov/pubmed/9480981
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