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Opposite Roles of FAP-1 and Dynamin in the Regulation of Fas (CD95) Translocation to the Cell Surface and Susceptibility to Fas Ligand-mediated Apoptosis

Human melanoma is the most aggressive form of skin cancer and is extremely resistant to radiation and chemotherapy. One of the critical parameters of this resistance is down-regulation of Fas (CD95) cell-surface expression. Using TIG3 normal human fibro-blasts and human melanoma cell lines, we inves...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Ivanov, Vladimir N., Ronai, Ze'ev, Hei, Tom K.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376329/
https://ncbi.nlm.nih.gov/pubmed/16306044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M509866200
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