Reelin Deficiency and Displacement of Mature Neurons, But Not Neurogenesis, Underlie the Formation of Granule Cell Dispersion in the Epileptic Hippocampus

Mesio-temporal lobe epilepsy (MTLE) is often accompanied by granule cell dispersion (GCD), a widening of the granule cell layer. The molecular determinants of GCD are poorly understood. Here, we used an animal model to study whether GCD results from an increased dentate neurogenesis associated with...

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Pubblicato in:J Neurosci
Autori principali: Heinrich, Christophe, Nitta, Naoki, Flubacher, Armin, Müller, Martin, Fahrner, Alexander, Kirsch, Matthias, Freiman, Thomas, Suzuki, Fumio, Depaulis, Antoine, Frotscher, Michael, Haas, Carola A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674063/
https://ncbi.nlm.nih.gov/pubmed/16641251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5516-05.2006
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