Reelin Deficiency and Displacement of Mature Neurons, But Not Neurogenesis, Underlie the Formation of Granule Cell Dispersion in the Epileptic Hippocampus

Mesio-temporal lobe epilepsy (MTLE) is often accompanied by granule cell dispersion (GCD), a widening of the granule cell layer. The molecular determinants of GCD are poorly understood. Here, we used an animal model to study whether GCD results from an increased dentate neurogenesis associated with...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Heinrich, Christophe, Nitta, Naoki, Flubacher, Armin, Müller, Martin, Fahrner, Alexander, Kirsch, Matthias, Freiman, Thomas, Suzuki, Fumio, Depaulis, Antoine, Frotscher, Michael, Haas, Carola A.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674063/
https://ncbi.nlm.nih.gov/pubmed/16641251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5516-05.2006
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