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Impaired Feedforward Inhibition of the Thalamocortical Projection in Epileptic Ca(2+) Channel Mutant Mice, tottering

The tottering (tg) mice have a mutation in the Ca(V)2.1 (P/Q-type) voltage-dependent Ca(2+) channel α(1)2.1 subunit gene. tg mice show not only cerebellar ataxia but also absence epilepsy, which begins at ∼3 weeks of age and persists throughout life. Similarities in EEG and sensitivity to antiepilep...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Sasaki, Sachie, Huda, Kadrul, Inoue, Tsuyoshi, Miyata, Mariko, Imoto, Keiji
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673963/
https://ncbi.nlm.nih.gov/pubmed/16540584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5422-05.2006
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