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Impaired Feedforward Inhibition of the Thalamocortical Projection in Epileptic Ca(2+) Channel Mutant Mice, tottering
The tottering (tg) mice have a mutation in the Ca(V)2.1 (P/Q-type) voltage-dependent Ca(2+) channel α(1)2.1 subunit gene. tg mice show not only cerebellar ataxia but also absence epilepsy, which begins at ∼3 weeks of age and persists throughout life. Similarities in EEG and sensitivity to antiepilep...
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| Publié dans: | J Neurosci |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673963/ https://ncbi.nlm.nih.gov/pubmed/16540584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5422-05.2006 |
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