GABA(A) Receptor γ2 Subunit Mutations Linked to Human Epileptic Syndromes Differentially Affect Phasic and Tonic Inhibition

GABA acts on GABA(A) receptors to evoke both phasic inhibitory synaptic events and persistent, tonic currents. The γ2 subunit of the GABA(A) receptor is involved in both phasic and tonic signaling in the hippocampus. Several mutations of this subunit are linked to human epileptic syndromes with febr...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Eugène, Emmanuel, Depienne, Christel, Baulac, Stéphanie, Baulac, Michel, Fritschy, Jean Marc, Le Guern, Eric, Miles, Richard, Poncer, Jean Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673514/
https://ncbi.nlm.nih.gov/pubmed/18094250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2618-07.2007
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