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Mosaic Removal of Hedgehog Signaling in the Adult SVZ Reveals That the Residual Wild-Type Stem Cells Have a Limited Capacity for Self-Renewal

The Smoothened gene is necessary for cells to transduce hedgehog signaling. Although we and others have previously shown that embryonic removal of Smoothened in the neural tube results in a loss of stem cells from the postnatal subventricular zone, it was unclear whether this reflected a requirement...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Balordi, Francesca, Fishell, Gord
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673442/
https://ncbi.nlm.nih.gov/pubmed/18160632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4531-07.2007
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