RGS9–2 Negatively Modulates l-3,4-Dihydroxyphenylalanine-Induced Dyskinesia in Experimental Parkinson's Disease

Chronic l-dopa treatment of Parkinson's disease (PD) often leads to debilitating involuntary movements, termed l-dopa-induced dyskinesia (LID), mediated by dopamine (DA) receptors. RGS9–2 is a GTPase accelerating protein that inhibits DA D2 receptor-activated G proteins. Herein, we assess the f...

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Publicado en:J Neurosci
Main Authors: Gold, Stephen J., Hoang, Chau V., Potts, Bryan W., Porras, Gregory, Pioli, Elsa, Kim, Ki Woo, Nadjar, Agnes, Qin, Chuan, LaHoste, Gerald J., Li, Qin, Bioulac, Bernard H., Waugh, Jeffrey L., Gurevich, Eugenia, Neve, Rachael L., Bezard, Erwan
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673430/
https://ncbi.nlm.nih.gov/pubmed/18160641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4223-07.2007
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