RGS9–2 Negatively Modulates l-3,4-Dihydroxyphenylalanine-Induced Dyskinesia in Experimental Parkinson's Disease

Chronic l-dopa treatment of Parkinson's disease (PD) often leads to debilitating involuntary movements, termed l-dopa-induced dyskinesia (LID), mediated by dopamine (DA) receptors. RGS9–2 is a GTPase accelerating protein that inhibits DA D2 receptor-activated G proteins. Herein, we assess the f...

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Publié dans:J Neurosci
Auteurs principaux: Gold, Stephen J., Hoang, Chau V., Potts, Bryan W., Porras, Gregory, Pioli, Elsa, Kim, Ki Woo, Nadjar, Agnes, Qin, Chuan, LaHoste, Gerald J., Li, Qin, Bioulac, Bernard H., Waugh, Jeffrey L., Gurevich, Eugenia, Neve, Rachael L., Bezard, Erwan
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673430/
https://ncbi.nlm.nih.gov/pubmed/18160641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4223-07.2007
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