A Promising Therapeutic Approach for Multiple Sclerosis: Recombinant T-Cell Receptor Ligands Modulate Experimental Autoimmune Encephalomyelitis by Reducing Interleukin-17 Production and Inhibiting Migration of Encephalitogenic Cells into the CNS

Recombinant T-cell receptor ligands (RTLs) can prevent and reverse clinical and histological signs of experimental autoimmune encephalomyelitis (EAE) in an antigen-specific manner and are currently in clinical trials for treatment of subjects with multiple sclerosis (MS). To evaluate regulatory mech...

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Publicat a:J Neurosci
Autors principals: Sinha, Sushmita, Subramanian, Sandhya, Proctor, Thomas M., Kaler, Laurie J., Grafe, Marjorie, Dahan, Rony, Huan, Jianya, Vandenbark, Arthur A., Burrows, Gregory G., Offner, Halina
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2007
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673319/
https://ncbi.nlm.nih.gov/pubmed/18003831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3599-07.2007
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