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Profound Decreases in Dopamine Release in Striatum in Detoxified Alcoholics: Possible Orbitofrontal Involvement

The value of rewards (natural rewards and drugs) is associated with dopamine increases in the nucleus accumbens and varies as a function of context. The prefrontal cortex has been implicated in the context dependency of rewards and in the fixated high value that drugs have in addiction, although the...

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Pubblicato in:J Neurosci
Autori principali: Volkow, Nora D., Wang, Gene-Jack, Telang, Frank, Fowler, Joanna S., Logan, Jean, Jayne, Millard, Ma, Yeming, Pradhan, Kith, Wong, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673312/
https://ncbi.nlm.nih.gov/pubmed/18003850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3371-07.2007
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