Wird geladen...

Loss of X-Linked Mental Retardation Gene Oligophrenin1 in Mice Impairs Spatial Memory and Leads to Ventricular Enlargement and Dendritic Spine Immaturity

Loss of oligophrenin1 (OPHN1) function in human causes X-linked mental retardation associated with cerebellar hypoplasia and, in some cases, with lateral ventricle enlargement. In vitro studies showed that ophn1 regulates dendritic spine through the control of Rho GTPases, but its in vivo function r...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Khelfaoui, Malik, Denis, Cécile, van Galen, Elly, de Bock, Frédéric, Schmitt, Alain, Houbron, Christophe, Morice, Elise, Giros, Bruno, Ramakers, Ger, Fagni, Laurent, Chelly, Jamel, Nosten-Bertrand, Marika, Billuart, Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673114/
https://ncbi.nlm.nih.gov/pubmed/17728457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2029-07.2007
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!