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Spinal Astrocyte Glutamate Receptor 1 Overexpression after Ischemic Insult Facilitates Behavioral Signs of Spasticity and Rigidity

Using a rat model of ischemic paraplegia, we examined the expression of spinal AMPA receptors and their role in mediating spasticity and rigidity. Spinal ischemia was induced by transient occlusion of the descending aorta combined with systemic hypotension. Spasticity/rigidity were identified by sim...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Hefferan, Michael P., Kucharova, Karolina, Kinjo, Kiyohiko, Kakinohana, Osamu, Sekerkova, Gabriella, Nakamura, Seiya, Fuchigami, Tatsuya, Tomori, Zoltan, Yaksh, Tony L., Kurtz, Neil, Marsala, Martin
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673044/
https://ncbi.nlm.nih.gov/pubmed/17942713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0989-07.2007
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