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Cyclooxygenase-1-Derived Prostaglandins in the Periaqueductal Gray Differentially Control C- versus A-Fiber-Evoked Spinal Nociception

Nonsteroidal anti-inflammatory drugs (NSAIDs) exert analgesic effects by inhibiting peripheral cyclooxygenases (COXs). It is now clear that these drugs also have central actions that include the modulation of descending control of spinal nociception from the midbrain periaqueductal gray (PAG). Desce...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Leith, J. Lianne, Wilson, Alex W., Donaldson, Lucy F., Lumb, Bridget M.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673041/
https://ncbi.nlm.nih.gov/pubmed/17942724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2586-07.2007
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