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Cyclooxygenase-1-Derived Prostaglandins in the Periaqueductal Gray Differentially Control C- versus A-Fiber-Evoked Spinal Nociception

Nonsteroidal anti-inflammatory drugs (NSAIDs) exert analgesic effects by inhibiting peripheral cyclooxygenases (COXs). It is now clear that these drugs also have central actions that include the modulation of descending control of spinal nociception from the midbrain periaqueductal gray (PAG). Desce...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Leith, J. Lianne, Wilson, Alex W., Donaldson, Lucy F., Lumb, Bridget M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673041/
https://ncbi.nlm.nih.gov/pubmed/17942724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2586-07.2007
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