Prefrontal Dysfunction in Schizophrenia Involves Mixed-Lineage Leukemia 1-Regulated Histone Methylation at GABAergic Gene Promoters

Alterations in GABAergic mRNA expression play a key role for prefrontal dysfunction in schizophrenia and other neurodevelopmental disease. Here, we show that histone H3-lysine 4 methylation, a chromatin mark associated with the transcriptional process, progressively increased at GAD1 and other GABAe...

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Pubblicato in:J Neurosci
Autori principali: Huang, Hsien-Sung, Matevossian, Anouch, Whittle, Catheryne, Kim, Se Young, Schumacher, Armin, Baker, Stephen P., Akbarian, Schahram
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2007
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673022/
https://ncbi.nlm.nih.gov/pubmed/17942719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3272-07.2007
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