cAMP Response Element-Binding Protein Deficiency Allows for Increased Neurogenesis and a Rapid Onset of Antidepressant Response

cAMP response element-binding protein (CREB) has been implicated in the molecular and cellular mechanisms of chronic antidepressant (AD) treatment, although its role in the behavioral response is unclear. CREB-deficient (CREB(αΔ) mutant) mice demonstrate an antidepressant phenotype in the tail suspe...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Gur, Tamar L., Conti, Alana C., Holden, Jessica, Bechtholt, Anita J., Hill, Tiffany E., Lucki, Irwin, Malberg, Jessica E., Blendy, Julie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2007
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672880/
https://ncbi.nlm.nih.gov/pubmed/17634380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2051-07.2007
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