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Increased Hippocampal Neurogenesis and Accelerated Response to Antidepressants in Mice with Specific Deletion of CREB in the Hippocampus: Role of cAMP Response-Element Modulator τ

The transcription factor cAMP response element-binding protein (CREB) has been implicated in the pathophysiology of depression as well as in the efficacy of antidepressant treatment. However, altering CREB levels appears to have differing effects on anxiety- and depression-related behaviors, dependi...

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Detalhes bibliográficos
Main Authors: Gundersen, Brigitta B., Briand, Lisa A., Onksen, Jennifer L., LeLay, John, Kaestner, Klaus H., Blendy, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755714/
https://ncbi.nlm.nih.gov/pubmed/23966689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1669-13.2013
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