Inhibition of Rho via Arg and p190RhoGAP in the Postnatal Mouse Hippocampus Regulates Dendritic Spine Maturation, Synapse and Dendrite Stability, and Behavior

The RhoA (Rho) GTPase is a master regulator of dendrite morphogenesis. Rho activation in developing neurons slows dendrite branch dynamics, yielding smaller, less branched dendrite arbors. Constitutive activation of Rho in mature neurons causes dendritic spine loss and dendritic regression, indicati...

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Publicado en:J Neurosci
Autores principales: Sfakianos, Mindan K., Eisman, Aaron, Gourley, Shannon L., Bradley, William D., Scheetz, Alfred J., Settleman, Jeffrey, Taylor, Jane R., Greer, Charles A., Williamson, Anne, Koleske, Anthony J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2007
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672862/
https://ncbi.nlm.nih.gov/pubmed/17928439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0793-07.2007
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