Inhibition of Rho via Arg and p190RhoGAP in the Postnatal Mouse Hippocampus Regulates Dendritic Spine Maturation, Synapse and Dendrite Stability, and Behavior

The RhoA (Rho) GTPase is a master regulator of dendrite morphogenesis. Rho activation in developing neurons slows dendrite branch dynamics, yielding smaller, less branched dendrite arbors. Constitutive activation of Rho in mature neurons causes dendritic spine loss and dendritic regression, indicati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Sfakianos, Mindan K., Eisman, Aaron, Gourley, Shannon L., Bradley, William D., Scheetz, Alfred J., Settleman, Jeffrey, Taylor, Jane R., Greer, Charles A., Williamson, Anne, Koleske, Anthony J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2007
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672862/
https://ncbi.nlm.nih.gov/pubmed/17928439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0793-07.2007
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