Human Immunodeficiency Virus-1/Surface Glycoprotein 120 Induces Apoptosis through RNA-Activated Protein Kinase Signaling in Neurons

Previous work has demonstrated that the surface glycoprotein (gp120) of human immunodeficiency virus-1 (HIV-1) can induce damage and apoptosis of neurons both in vitro and in vivo. In this report, we provide evidence that double-stranded RNA-activated protein kinase (PKR), a stress kinase, is involv...

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Pubblicato in:J Neurosci
Autori principali: Alirezaei, Mehrdad, Watry, Debbie D., Flynn, Claudia F., Kiosses, William B., Masliah, Eliezer, Williams, Bryan R. G., Kaul, Marcus, Lipton, Stuart A., Fox, Howard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672852/
https://ncbi.nlm.nih.gov/pubmed/17928446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2733-07.2007
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