Identification of a Novel Endocannabinoid-Hydrolyzing Enzyme Expressed by Microglial Cells

The endocannabinoids (eCBs) anandamide and 2-arachidonoyl glycerol (2-AG) are inactivated by a two-step mechanism. First, they are carried into cells, and then anandamide is hydrolyzed by fatty acid amide hydrolase (FAAH) and 2-AG by monoacylglycerol lipase (MGL). Here we provide evidence for a prev...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Muccioli, Giulio G., Xu, Cong, Odah, Emma, Cudaback, Eiron, Cisneros, Jose Antonio, Lambert, Didier M., López Rodríguez, María Luz, Bajjalieh, Sandra, Stella, Nephi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672592/
https://ncbi.nlm.nih.gov/pubmed/17360910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4830-06.2007
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