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Mice Lacking Protease Nexin-1 Show Delayed Structural and Functional Recovery after Sciatic Nerve Crush

Multiple molecular mechanisms influence nerve regeneration. Because serine proteases were shown to affect peripheral nerve regeneration, we performed nerve crush experiments to study synapse reinnervation in adult mice lacking the serpin protease nexin-1 (PN-1). PN-1 is a potent endogenous inhibitor...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lino, Maria Maddalena, Atanasoski, Suzana, Kvajo, Mirna, Fayard, Bérengère, Moreno, Eliza, Brenner, Hans Rudolf, Suter, Ueli, Monard, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672422/
https://ncbi.nlm.nih.gov/pubmed/17409231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0277-07.2007
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