Rapid Synapse Elimination after Postsynaptic Protein Synthesis Inhibition In Vivo

To examine the role of retrograde signals on synaptic maintenance, we inhibited protein synthesis in individual postsynaptic cells in vivo while monitoring presynaptic terminals. Within 12 h, axon terminals begin to atrophy and withdraw from normal postsynaptic sites. Structural similarities between...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: McCann, Corey M., Nguyen, Quyen T., Santo Neto, Humberto, Lichtman, Jeff W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2007
Gaiak:
Brief Communications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672258/
https://ncbi.nlm.nih.gov/pubmed/17537978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0627-07.2007
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