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Overexpressing the Glucocorticoid Receptor in Forebrain Causes an Aging-Like Neuroendocrine Phenotype and Mild Cognitive Dysfunction

Repeated stress enhances vulnerability to neural dysfunction that is cumulative over the course of the lifespan. This dysfunction contributes to cognitive deficits observed during aging. In addition, aging is associated with dysregulation of the limbic–hypothalamic–pituitary–adrenal (LHPA) axis, lea...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wei, Qiang, Hebda-Bauer, Elaine K., Pletsch, Amy, Luo, Jie, Hoversten, Mary T., Osetek, Andrew J., Evans, Simon J., Watson, Stanley J., Seasholtz, Audrey F., Akil, Huda
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672178/
https://ncbi.nlm.nih.gov/pubmed/17699665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0910-07.2007
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