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Neuron-Specific Inactivation of the Hypoxia Inducible Factor 1α Increases Brain Injury in a Mouse Model of Transient Focal Cerebral Ischemia

In the present study, we show a biphasic activation of hypoxia inducible factor 1α (HIF-1) after stroke that lasts for up to 10 d, suggesting the involvement of the HIF pathway in several aspects of the pathophysiology of cerebral ischemia. We provide evidence that HIF-1-mediated responses have an o...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Baranova, Oxana, Miranda, Luis F., Pichiule, Paola, Dragatsis, Ioannis, Johnson, Randall S., Chavez, Juan C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672155/
https://ncbi.nlm.nih.gov/pubmed/17554006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0449-07.2007
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