Biphasic Coupling of Neuronal Nitric Oxide Synthase Phosphorylation to the NMDA Receptor Regulates AMPA Receptor Trafficking and Neuronal Cell Death

Postsynaptic nitric oxide (NO) production affects synaptic plasticity and neuronal cell death. Ca(2+) fluxes through the NMDA receptor (NMDAR) stimulate the production of NO by neuronal nitric oxide synthase (nNOS). However, the mechanisms by which nNOS activity is regulated are poorly understood. W...

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Pubblicato in:J Neurosci
Autori principali: Rameau, Gerald A., Tukey, David S., Garcin-Hosfield, Elsa D., Titcombe, Roseann F., Misra, Charu, Khatri, Latika, Getzoff, Elizabeth D., Ziff, Edward B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2007
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672118/
https://ncbi.nlm.nih.gov/pubmed/17392461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4799-06.2007
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