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Cannabinoids Excite Hypothalamic Melanin-Concentrating Hormone But Inhibit Hypocretin/Orexin Neurons: Implications for Cannabinoid Actions on Food Intake and Cognitive Arousal

Cannabinoids modulate energy homeostasis and decrease cognitive arousal, possibly by acting on hypothalamic neurons including those that synthesize melanin-concentrating hormone (MCH) or hypocretin/orexin. Using patch-clamp recordings, we compared the actions of cannabinoid agonists and antagonists...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Huang, Hao, Acuna-Goycolea, Claudio, Li, Ying, Cheng, H. M., Obrietan, Karl, van den Pol, Anthony N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672093/
https://ncbi.nlm.nih.gov/pubmed/17475795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0732-07.2007
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