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The I–II Loop Controls Plasma Membrane Expression and Gating of Ca(v)3.2 T-Type Ca(2+) Channels: A Paradigm for Childhood Absence Epilepsy Mutations
Calcium currents via low-voltage-activated T-type channels mediate burst firing, particularly in thalamic neurons. Considerable evidence supports the hypothesis that overactive T-channels may contribute to thalamocortical dysrhythmia, including absence epilepsy. Single nucleotide polymorphisms in on...
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| Publicado no: | J Neurosci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672065/ https://ncbi.nlm.nih.gov/pubmed/17215393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1817-06.2007 |
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