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The I–II Loop Controls Plasma Membrane Expression and Gating of Ca(v)3.2 T-Type Ca(2+) Channels: A Paradigm for Childhood Absence Epilepsy Mutations

Calcium currents via low-voltage-activated T-type channels mediate burst firing, particularly in thalamic neurons. Considerable evidence supports the hypothesis that overactive T-channels may contribute to thalamocortical dysrhythmia, including absence epilepsy. Single nucleotide polymorphisms in on...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Neurosci
मुख्य लेखकों: Vitko, Iuliia, Bidaud, Isabelle, Arias, Juan Manuel, Mezghrani, Alexandre, Lory, Philippe, Perez-Reyes, Edward
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Neuroscience 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672065/
https://ncbi.nlm.nih.gov/pubmed/17215393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1817-06.2007
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