Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop

Voltage-dependent calcium channels (Cav) of the T-type family (Cav3.1, Cav3.2, and Cav3.3) are activated by low threshold membrane depolarization and contribute greatly to neuronal network excitability. Enhanced T-type channel activity, especially Cav3.2, contributes to disease states, including abs...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Monteil, Arnaud, Chausson, Patrick, Boutourlinsky, Katia, Mezghrani, Alexandre, Huc-Brandt, Sylvaine, Blesneac, Iulia, Bidaud, Isabelle, Lemmers, Céline, Leresche, Nathalie, Lambert, Régis C., Lory, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481217/
https://ncbi.nlm.nih.gov/pubmed/25931121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634261
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