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The orphan nuclear receptor SHP regulates ER stress response by inhibiting XBP1s degradation
The orphan nuclear receptor SHP (small heterodimer partner) is a well-known transcriptional corepressor of bile acid and lipid metabolism in the liver; however, its function in other tissues is poorly understood. Here, we report an unexpected role for SHP in the exocrine pancreas as a modulator of t...
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| Publicado en: | Genes Dev |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672048/ https://ncbi.nlm.nih.gov/pubmed/31296559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.326868.119 |
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