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Allostatic adaptation and personalized physiological trade-offs in the circadian regulation of the HPA axis: A mathematical modeling approach

The hypothalamic-pituitary-adrenal (HPA) axis orchestrates the physiological response to unpredictable acute stressors. Moreover, the HPA axis exhibits prominent circadian activity and synchronizes peripheral circadian clocks to daily environmental cycles, thereby promoting homeostasis. Persistent d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rao, Rohit, Androulakis, Ioannis P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671996/
https://ncbi.nlm.nih.gov/pubmed/31371802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47605-7
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