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Physiologically-based Pharmacokinetic Models: Approaches for Enabling Personalized Medicine

Personalized medicine strives to deliver the ‘right drug at the right dose’ by considering inter-person variability, one of the causes for therapeutic failure in specialized populations of patients. Physiologically-based Pharmacokinetic (PBPK) modeling is a key tool in the advancement of personalize...

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Detalles Bibliográficos
Publicado en:J Pharmacokinet Pharmacodyn
Autores principales: Hartmanshenn, Clara, Scherholz, Megerle, Androulakis, Ioannis P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204363/
https://ncbi.nlm.nih.gov/pubmed/27647273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-016-9492-y
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