Successful application of prime and pull strategy for a therapeutic HSV vaccine

One promising approach for a herpes simplex virus vaccine uses a vaccine to prime and a chemoattractant to pull immune cells into the genital tract. We evaluated subunit vaccines (prime) and imiquimod (pull) in the guinea pig (gp) model of recurrent Herpes simplex virus type-2 (HSV-2). Following vag...

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Bibliografiske detaljer
Udgivet i:NPJ Vaccines
Main Authors: Bernstein, David I., Cardin, Rhonda D., Bravo, Fernando J., Awasthi, Sita, Lu, Peiwen, Pullum, Derek A., Dixon, David A., Iwasaki, Akiko, Friedman, Harvey M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671986/
https://ncbi.nlm.nih.gov/pubmed/31396405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-019-0129-1
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