NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer

Cancer cells, particularly in solid tumors, are surrounded by non-neoplastic elements, including endothelial and stromal cells, as well as cells of immune origin, which can support tumor growth by providing the right conditions. On the other hand, local hypoxia, and lack of nutrients induce tumor ce...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Audrito, Valentina, Managò, Antonella, Gaudino, Federica, Sorci, Leonardo, Messana, Vincenzo Gianluca, Raffaelli, Nadia, Deaglio, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671870/
https://ncbi.nlm.nih.gov/pubmed/31402913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01720
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