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Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics

The discovery of polymyxins, highly basic lipodecapeptides, was published independently by three laboratories in 1947. Their clinical use, however, was abandoned in the sixties because of nephrotoxicity and because better-tolerated drugs belonging to other antibiotic classes were discovered. Now pol...

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Bibliografski detalji
Izdano u:Front Microbiol
Glavni autor: Vaara, Martti
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671869/
https://ncbi.nlm.nih.gov/pubmed/31404242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01689
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