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Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics
The discovery of polymyxins, highly basic lipodecapeptides, was published independently by three laboratories in 1947. Their clinical use, however, was abandoned in the sixties because of nephrotoxicity and because better-tolerated drugs belonging to other antibiotic classes were discovered. Now pol...
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| Publicado no: | Front Microbiol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6671869/ https://ncbi.nlm.nih.gov/pubmed/31404242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01689 |
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