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Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics

The discovery of polymyxins, highly basic lipodecapeptides, was published independently by three laboratories in 1947. Their clinical use, however, was abandoned in the sixties because of nephrotoxicity and because better-tolerated drugs belonging to other antibiotic classes were discovered. Now pol...

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Bibliografische gegevens
Gepubliceerd in:Front Microbiol
Hoofdauteur: Vaara, Martti
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671869/
https://ncbi.nlm.nih.gov/pubmed/31404242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01689
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