The Clustering of GABA(A) Receptor Subtypes at Inhibitory Synapses is Facilitated via the Direct Binding of Receptor α2 Subunits to Gephyrin

Classical benzodiazepine sensitive GABA(A) receptor subtypes, the major mediators of fast synaptic inhibition in the brain are heteropentamers that can be assembled from α1–3/5, β1–3, and γ2 subunits, but how neurons orchestrate their selective accumulation at synapses remains obscure. We have ident...

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Udgivet i:J Neurosci
Main Authors: Tretter, Verena, Jacob, Tija C., Mukherjee, Jayanta, Fritschy, Jean-Marc, Pangalos, Menelas N., Moss, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2008
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671568/
https://ncbi.nlm.nih.gov/pubmed/18256255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5050-07.2008
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