Mitochondrial Reactive Oxygen Species Inactivate Neuronal Nicotinic Acetylcholine Receptors and Induce Long-Term Depression of Fast Nicotinic Synaptic Transmission

Neuronal nicotinic acetylcholine receptors (nAChRs), ligand-gated ion channels implicated in a variety of cognitive, motor, and sensory behaviours, are targeted to compartments rich in mitochondria, particularly postsynaptic domains and presynaptic terminals, exposing these receptors to reactive oxy...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Campanucci, Verónica A., Krishnaswamy, Arjun, Cooper, Ellis
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671543/
https://ncbi.nlm.nih.gov/pubmed/18272694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5130-07.2008
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