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Reactive oxygen species inactivate neuronal nicotinic acetylcholine receptors through a highly conserved cysteine near the intracellular mouth of the channel: implications for diseases that involve oxidative stress
ABSTRACT: An intriguing feature of several nicotinic acetylcholine receptors (nAChRs) on neurons is that their subunits contain a highly conserved cysteine residue located near the intracellular mouth of the receptor pore. The work summarized in this review indicates that α3β4-containing and α4β2-co...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300044/ https://ncbi.nlm.nih.gov/pubmed/21969449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.214007 |
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