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Hypoxia-Inducible Factor-1α Protects Cultured Cortical Neurons from Lipopolysaccharide-Induced Cell Death via Regulation of NR1 Expression

Inflammation is involved in some neurodegenerative disorders. NMDA glutamate receptors play an important role in neuronal development. Here, we show that NR1 expression in the cerebral cortex and primary neurons of rats was upregulated after lipopolysaccharide (LPS) treatment. This increase in NR1 e...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Yeh, Shiu-Hwa, Hung, Jan-Jong, Gean, Po-Wu, Chang, Wen-Chang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671468/
https://ncbi.nlm.nih.gov/pubmed/19109507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4258-08.2008
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