Serotonin Hyperinnervation Abolishes Seizure Susceptibility in Otx2 Conditional Mutant Mice

The homeobox-containing transcription factor Otx2 is crucially involved in fate determination of midbrain neurons. Mutant mice, in which Otx2 was conditionally inactivated by a Cre recombinase expressed under the transcriptional control of the Engrailed1 (En1) gene (En1(cre/+); Otx2(flox/flox)), sho...

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Vydáno v:J Neurosci
Hlavní autoři: Tripathi, Prem Prakash, Di Giovannantonio, Luca Giovanni, Viegi, Alessandro, Wurst, Wolfgang, Simeone, Antonio, Bozzi, Yuri
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2008
Témata:
Brief Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670936/
https://ncbi.nlm.nih.gov/pubmed/18784307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2208-08.2008
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