Developmental Neuronal Death in Hippocampus Requires the Microglial CD11b Integrin and DAP12 Immunoreceptor

In several brain regions, microglia actively promote neuronal apoptosis during development. However, molecular actors leading microglia to trigger death remain mostly unknown. Here, we show that, in the developing hippocampus, apoptotic neurons are contacted by microglia expressing both the integrin...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Wakselman, Shirley, Béchade, Catherine, Roumier, Anne, Bernard, Delphine, Triller, Antoine, Bessis, Alain
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2008
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670768/
https://ncbi.nlm.nih.gov/pubmed/18685038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1006-08.2008
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