Macrophage-Derived Tumor Necrosis Factor α, an Early Developmental Signal for Motoneuron Death

Mechanisms inducing neuronal death at defined times during embryogenesis remain enigmatic. We show in explants that a developmental switch occurs between embryonic day 12 (E12) and E13 in rats that is 72-48 hr before programmed cell death. Half the motoneurons isolated from peripheral tissues at E12...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Sedel, Frédéric, Béchade, Catherine, Vyas, Sheela, Triller, Antoine
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Development/Plasticity/Repair
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730439/
https://ncbi.nlm.nih.gov/pubmed/14999074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4464-03.2004
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